Glutathione Whitening Treatment, also known as IU Injection

What is Glutathione?

Glutathione is abundantly present in various organs of our body, such as the liver, kidneys, and brain, and is one of the main antioxidant components.

This component helps reduce cell damage by removing reactive oxygen species (ROS) and aids in reactivating other antioxidant substances like vitamins C and E. It is known as a substance that contributes to cell protection and healthy aging.

The Impact of Glutathione on Skin Brightening

Beyond its simple antioxidant action, glutathione plays a role in making the skin tone clearer and more even.

Inhibition of Tyrosinase Enzyme Activity

Glutathione can help prevent excessive hyperpigmentation by inhibiting the action of tyrosinase, an enzyme that induces melanin production.

Inducing Changes in Melanin Pigment Type

It works to increase the production of relatively lighter phaeomelanin rather than dark, dense eumelanin, thereby allowing one to expect an overall brighter skin tone.

Managing Pigment Production through Antioxidant Action

When reactive oxygen species are generated due to UV exposure, heat, or inflammatory reactions, melanin production can be promoted. Glutathione can neutralize these reactive oxygen species and contribute to preventing the occurrence of hyperpigmentation.

Synergistic Effect with Vitamin C

Vitamin C helps glutathione function by reactivating oxidized glutathione. Glutathione inhibits melanin synthesis, and this interaction creates an effective environment for skin brightening.

In summary: Glutathione regulates melanin production and promotes lighter types of melanin, which can help improve skin tone naturally and evenly.

Why is Glutathione Treatment Special Here?

Many of you may have encountered glutathione through oral intake or injection treatments, but these methods have several considerations.

Limitations of Oral Glutathione Intake

Oral glutathione tends to have a low absorption rate in the gastrointestinal tract, and most of it is processed by the liver after intake, so the actual amount reaching the skin may not be significant.

Therefore, some believe that it might be difficult to immediately experience skin tone improvement effects solely through oral intake.

Characteristics of Intravenous Injection Treatment

Intravenous injections distribute the ingredients evenly throughout the body, making it difficult to deliver them concentratedly to specific areas.

While it can be helpful for liver function support or systemic antioxidant effects, if the goal is to improve facial hyperpigmentation or skin tone, localized effects may be difficult to achieve.

Our Differentiating Approach to Glutathione Treatment

Utilizing Iontophoresis: We adopt a method that uses electric current to effectively deliver glutathione beyond the skin barrier and into the dermis. This method can complement the limitations of oral intake or injection treatments.

Targeted Localized Management: Instead of spreading glutathione throughout the entire body, we focus on inducing ingredient absorption only in facial areas requiring hyperpigmentation or skin tone management.

Using Undiluted Glutathione Concentrate: Considering the ingredient's efficacy during treatment, we aim to deliver antioxidant and brightening effects more effectively by using undiluted 100% glutathione concentrate ampoules.

Here, we structure our glutathione care program, considering it as a “more direct and targeted treatment than oral intake or injection procedures.”

Reasons for Absorption via Iontophoresis

Limitations of Oral Glutathione: When taken orally, absorption rates in the gastrointestinal tract can be inconsistent, and a significant portion may be metabolized by the liver, potentially leading to insufficient amounts reaching the skin.

Limitations of Topical Application: The stratum corneum on the skin's surface acts as a barrier, protecting the skin from external substances. Therefore, water-soluble ingredients like glutathione may find it difficult to penetrate deeply by simply applying them to the skin.

Key Principles of Iontophoresis:

Principle of Electrical Repulsion: It utilizes an electric current of the same charge to repel negatively charged glutathione, inducing its penetration beyond the skin's protective barrier.

Electro-osmosis: It creates a subtle fluid flow, forming pathways that allow active ingredients to be better absorbed into the skin.

Ingredient Delivery to the Dermis: Rather than just staying on the surface, it is possible to effectively deliver active ingredients close to the skin's dermis.

In conclusion, iontophoresis is a method of absorbing active ingredients into the skin “more directly than oral intake, and more deeply than simple topical application”.

Treatment Intervals and Recommended Sessions

Recommended Interval: Generally, treatment once every week can be considered.

Recommended Sessions: For optimal results, consistent treatment of at least 5 sessions may be beneficial.

Follow-up Care: Regular supplementary treatments can be helpful for maintaining a consistent skin tone.