Key Features of EYE Endran

• Recently, various PN skin boosters with similar ingredients have been released. EYE Endran has the same PN ingredient content as a specific original product and uses PN ingredients extracted from salmon. It is also relatively affordable, making it a good option for those considering consistent eye area care. Since there may be differences from PN extracted from trout or other fish, it is recommended to check if the raw material is salmon-derived.
• The treatment can be performed not only under the eyes but also on delicate areas such as the eyelids and the immediate side of the eyes. We adjust the depth of the skin layer in the desired area to perform a customized micro-papule (embossing) treatment.
• We use the full 2cc of PN ingredient without saline dilution, delivering the complete effect of the ingredient.
• Its low viscosity can help reduce pain during treatment, and any micro-papules (embossing) that appear after injection tend to be absorbed relatively quickly.
• Developed specifically for the eye area, it is designed for stable treatment even on sensitive skin around the eyes.
• Despite being an eye-specific product, it causes minimal pain, so full-face treatment can also be considered. It can help improve overall skin dullness, inner dryness, and fine wrinkles.
• Based on clinical expertise in acupuncture and injection procedures, we can precisely inject PN ingredients into the dermal layer. After the treatment, we personally confirm the micro-papules (embossing) in the eye area with the patient and provide explanations.

What is EYE Endran (PN) Skin Booster?

EYE Endran is a PN (Polynucleotide) ingredient-based skin booster developed considering the characteristics of the delicate skin around the eyes.

It is used as a precise treatment that can help improve concerns such as fine wrinkles, dark circles, and inner dryness around the eyes.

While having similar PN ingredients and content as existing PN skin booster products, it is specially designed for the thin and sensitive skin around the eyes. Thanks to its smooth injection feel, it can help reduce pain during treatment, and the micro-papules (embossing) tend to subside relatively quickly.

Why is EYE Endran Needed for the Eye Area?

The skin around the eyes is particularly thin and sensitive compared to other areas of the face.

Due to these characteristics, it is vulnerable to external stimuli, and changes due to aging or dryness tend to appear earlier than in other areas.

In particular, the skin barrier function is often weakened, leading to a high incidence of inner dryness, fine wrinkles, and bluish dark circles due to visible blood vessels.

However, due to the structural characteristics of the eye area, which has less subcutaneous fat and a thin dermal layer, there may be limitations to improvement with general moisturizers or eye creams alone.

Therefore, it is believed that injecting PN ingredients directly into the dermal layer to induce skin regeneration can provide significant help in improving eye area concerns.

Explanation of PN (Polynucleotide) Ingredient

PN is a high-purity, biocompatible substance extracted from salmon DNA.

Compared to PDRN, it has a relatively larger molecular weight and is known as an ingredient that can further contribute to inducing responses in the dermal layer, thereby helping with continuous improvement of the skin environment.

Simply put, while PDRN primarily focuses on basic hydration and skin regeneration, PN can be seen as playing a role that concentrates more on fundamental improvement of skin structure by directly activating the dermal layer.

PN acts in the following ways to improve skin:

It stimulates fibroblasts in the skin to promote collagen and elastin production. This helps enhance skin elasticity and reduce fine wrinkles, contributing to a more supple and healthy overall skin surface.

It increases the secretion of various growth factors such as TGF, FGF, and VEGF, promoting skin recovery processes. This can aid in the regeneration of damaged tissues and reduce inflammatory responses, helping to maintain healthy skin.

It induces epidermal cell regeneration and strengthens skin barrier function. This can increase the cohesion between keratinocytes, suppress moisture loss, and help improve inner dryness.

The skin forms a barrier structure composed of keratinocytes, which act as bricks, and intercellular lipids, which act as cement connecting them.

PN helps restore this "cement" role, which can positively impact preventing skin moisture evaporation and simultaneously alleviating inner dryness and sensitivity.

It helps repair damaged dermal tissue and subtly increases dermal thickness. This can contribute to alleviating dark circles caused by thinning dermis and improving fine wrinkles.

The skin barrier is composed of keratinocytes and intercellular lipids. PN can help improve the function of these intercellular lipids, preventing moisture loss and simultaneously reducing inner dryness and skin sensitivity.

Meaning of Micro-papule (Embossing) and Dermal Layer Injection

The dermal layer has a relatively narrow space due to its tissue structure.

When medication is injected into such areas, a temporary swelling of the skin may occur.

This phenomenon is called a micro-papule (or "embossing"), and it is one indicator that the medication has precisely reached the intended dermal layer.

At our clinic, we confirm the micro-papules (embossing) with the patient after the treatment and provide a detailed explanation of the treatment progress.

While micro-papules from other PN products may last for 3-7 days, EYE Endran has a relatively lower viscosity, so they tend to be absorbed and disappear quickly, mostly within 1 week. Additionally, the treatment causes less pain, allowing for a relatively comfortable experience even in sensitive areas like the eyes.

Cases Where EYE Endran May Be Considered

• Individuals who are starting to worry about fine wrinkles around the eyes.
• Individuals with bluish dark circles that make the under-eye area appear dark (When blood vessels are visible due to thin dermis, PN can help improve dermal thickness, contributing to dark circle reduction).
• Individuals who feel their skin texture is rough and makeup doesn't apply well due to inner dryness.
• This treatment can be considered for individuals with thin and sensitive skin, where careful selection of lifting procedures is necessary.
• It may be suitable for those who feel that using conventional eye creams alone does not sufficiently improve the eye area.
• If you have been concerned about the possibility of treatment due to fine wrinkles on the delicate eyelid area, you can confirm its suitability through a consultation.
• This treatment can also be beneficial if fine lines around your eyes make you conscious of your expressions.

Treatment Interval and Duration of Effect

• We generally recommend considering a total of three treatments, spaced one month apart.
• After that, receiving maintenance treatments approximately every 6 months can help sustain the effects.
• Generally, the treatment effects can last from 6 months to 1 year, though individual results may vary.
• Discomfort during the treatment is generally less than with conventional Rejuran treatments. Additionally, any temporary 'embossing' or bumps that may occur after the procedure usually subside naturally within 1 to 3 days.

Our Medical Team's Treatment Philosophy

Eye area treatments should focus not just on superficial wrinkle improvement, but more importantly on activating the skin's inherent regenerative and restorative capabilities.

When consistent use of eye creams doesn't bring satisfactory changes, Eye Endran treatment can offer a different approach.

There may come a time when topical skincare alone is not enough to adequately address concerns about the skin around the eyes.

In such cases, it is advisable to first consider the internal health of the skin. Treatments that help improve the density and thickness of the dermal layer can be an effective solution.

Eye Endran treatment can be considered as one of the starting points for these changes.

Skin treatments go beyond mere technical aspects; the delicate approach and responsibility of the medical team are paramount.

Our role is not only to ensure precise injection but also to meticulously check every step of the treatment process and carefully monitor the patient's satisfaction.

Our medical team will build all these processes together with patients, based on trust.